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dnbseq g400 sequencer  (Complete Genomics Inc)


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    Structured Review

    Complete Genomics Inc dnbseq g400 sequencer
    Dnbseq G400 Sequencer, supplied by Complete Genomics Inc, used in various techniques. Bioz Stars score: 99/100, based on 2095 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnbseq+g400+sequencer/DNBSEQ-G400/nct06227728-13-10-12
    Average 99 stars, based on 2095 article reviews
    dnbseq g400 sequencer - by Bioz Stars, 2026-10
    99/100 stars

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    Related Articles

    Sequencing:

    Article Title: RHOBTB2-Associated Neurological Phenotypes and Underlying Mechanisms: Alternating Hemiplegia of Childhood Beyond ATP1A3
    Article Snippet: Genomic DNA was isolated from whole blood using a QIAamp DNA Blood Mini Kit (Qiagen, Hilden, Germany) and further analyzed by WES. .. The library preparation was performed according to the BGI WES Library construction kit protocol, and sequencing was performed with a DNBSEQ-G400 sequencer (MGI Tech, Shenzhen, China), with alignment and analysis performed against the GRCh38/hg38 reference genome assembly. .. Systematic interpretation of variants was performed as follows: All variants were prioritized using VarSome Clinical (Saphetor, Lausanne, Switzerland) and classified according to the recommendations of the American College of Medical Genetics and Genomics [20].

    Article Title: Analysis of PD-L1, TMB, MSI and Circulating Tumor DNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.
    Article Snippet: .. Massive parallel sequencing of DNA libraries was performed on the DNBSEQ-G400 sequencer (MGI, China) with an average depth of 500X for FFPE and 500X for WBC samples. ..

    Article Title: Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF.
    Article Snippet: .. Sequencing was performed on a DNBSEQ‐G400 sequencer (MGI Tech Co., ltd.) in 100‐base single‐read mode. ..

    Article Title: GDF15 promotes 5-Fluorouracil and Oxaliplatin resistance by promoting stem cell-like phenotype in colorectal cancer.
    Article Snippet: Library preparation was performed in accordance with the manufacturer’s instructions using a TruSeq stranded mRNA sample preparation kit (Illumina, USA). .. Sequencing was conducted using a DNBSEQ-G400 sequencer (MGI, China) in 100-base single-read mode. ..

    Article Title: Hypoxic CAF studies unveil PTHrP-vitamin D-RAS axis as pivotal in the CAF
    Article Snippet: .. Sequencing was performed on a DNBSEQ-G400 sequencer (MGI Tech Co., Ltd.) in 100-base single-read mode. ..

    Article Title: Metagenomic Evidence for Horizontal Gene Transfer and Functional Convergence in the Oral Microbiome of Cohabiting Dogs and Owners
    Article Snippet: Libraries were normalized to a concentration of 10 nM using the Qubit Fluorometer, pooled in equal volumes, and converted into DNA nanoballs (DNBs) via rolling-circle amplification using the DNBSEQ Library Prep Kit (MGI Tech, Shenzhen, China). .. The pooled DNBs were loaded onto a DNBSEQ-G400 flow cell and sequenced in paired-end 150 bp mode (PE150) on a DNBSEQ-G400 sequencer (MGI Tech, Shenzhen, China) in strict adherence to the manufacturer’s specifications for read length, cluster density, and sequencing chemistry. ..

    Article Title: Rare variants in embryonic development and cell signalling genes in syndromic and non-syndromic orofacial clefts: evidence from a Colombian Caribbean cohort.
    Article Snippet: .. Next generation paired-end sequencing was carried out using DNBSEQ Technology in a DNBSEQ-G400 sequencer (MGI®), which is based on the generation of DNA nanoballs (DNBs) for each DNA fragment created in the library and binding of each DNB on a patterned silicon chip. (https:// en.mgi-tech.com/products/resources). ..

    Formalin-fixed Paraffin-Embedded:

    Article Title: Analysis of PD-L1, TMB, MSI and Circulating Tumor DNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.
    Article Snippet: .. Massive parallel sequencing of DNA libraries was performed on the DNBSEQ-G400 sequencer (MGI, China) with an average depth of 500X for FFPE and 500X for WBC samples. ..

    Construct:

    Article Title: Hydrogen metabolism shapes gut microbiome into health-associated configurations
    Article Snippet: Quality controls were performed using Small Fragment kits on a Fragment Analyzer 5200 (Agilent Technologies), Quant-iT dsDNA and Qubit ssDNA Assay Kits (Thermo Fisher Scientific). .. Circularized library pools are constructed to optimize the yield of 20M paired-end reads (2 × 150) on a DNBseq G400 sequencer (MGI). .. Most steps are automated using Beckman Coulter and MGI pipetting handlers.

    Binding Assay:

    Article Title: Rare variants in embryonic development and cell signalling genes in syndromic and non-syndromic orofacial clefts: evidence from a Colombian Caribbean cohort.
    Article Snippet: .. Next generation paired-end sequencing was carried out using DNBSEQ Technology in a DNBSEQ-G400 sequencer (MGI®), which is based on the generation of DNA nanoballs (DNBs) for each DNA fragment created in the library and binding of each DNB on a patterned silicon chip. (https:// en.mgi-tech.com/products/resources). ..



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    Image Search Results


    Pedigree and mutation analysis of the family. (A) Pedigrees of the GS families. The square represents male, and the circle represents female. The arrow represents the proband. The shaded symbol represents a homozygous (HOM) patient, the unshaded symbol represents wild-type (WT) individuals, and the half-shaded symbol represents a heterozygous patient. Draw a diagonal line through the square or circle represents the member is deceased. Age (B) and Body Mass Index (BMI) (C) of GS homozygous patients ( n = 5) and wild type individuals ( n = 7), ** p < 0.01. (D) Sanger sequencing validation of the SLC12A3 mutation (c.1262G > T) in the GS patients.

    Journal: Renal Failure

    Article Title: Serum metabolic profiling analysis of Gitelman syndrome using untargeted metabolomics

    doi: 10.1080/0886022X.2026.2662094

    Figure Lengend Snippet: Pedigree and mutation analysis of the family. (A) Pedigrees of the GS families. The square represents male, and the circle represents female. The arrow represents the proband. The shaded symbol represents a homozygous (HOM) patient, the unshaded symbol represents wild-type (WT) individuals, and the half-shaded symbol represents a heterozygous patient. Draw a diagonal line through the square or circle represents the member is deceased. Age (B) and Body Mass Index (BMI) (C) of GS homozygous patients ( n = 5) and wild type individuals ( n = 7), ** p < 0.01. (D) Sanger sequencing validation of the SLC12A3 mutation (c.1262G > T) in the GS patients.

    Article Snippet: Whole-exome sequencing (WES) was performed on all patients using the MGISEQ-2000 platform (MGI Tech) and validated by Sanger sequencing.

    Techniques: Mutagenesis, Sequencing, Biomarker Discovery